Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

The respiratory chain in the majority of organisms with aerobic type metabolism features the
concomitant existence of the phosphorylating cytochrome pathway and the cyanide-and …

Paracoccidioidomycosis (PCM) is a deep systemic mycosis caused by human fungal
pathogens of the Paracoccidioides genus. The disease is geographically restricted to …

The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause
paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic …

We previously observed that hypoxia is an important component of host microenvironments
during pulmonary fungal infections. However, mechanisms of fungal growth in these in vivo …

In a large number of organisms covering all phyla, the mitochondrial respiratory chain
harbors, in addition to the conventional elements, auxiliary proteins that confer adaptive …

The role of the alternative respiratory pathway in the protection of plants against biotic stress
was examined in transgenic tobacco (Nicotiana attenuata) plants (irAOX) silenced in the …

The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS)
produced by host effector cells is a prerequisite to survive. To counteract these radicals …

Histoplasma capsulatum is a respiratory pathogen that infects phagocytic cells. The
mechanisms allowing Histoplasma to overcome toxic reactive oxygen molecules produced …

The alternative oxidase (AOX) is a ubiquitous terminal oxidase of plants and many fungi,
catalyzing the four‐electron reduction of oxygen to water alongside the cytochrome‐based …