Ever since the beginning of biochemical analysis, yeast has been a pioneering model for
studying the regulation of eukaryotic metabolism. During the last three decades, the …

Dramatic accumulation of proline due to increased synthesis and decreased degradation
under a variety of stress conditions such as salt, drought and metal has been documented in …

Proline accumulation and metabolism are associated with mechanisms of abiotic stress
avoidance in plants. Proline accumulation generally improves osmotic stress tolerance …

Proline fulfils diverse functions in plants. As amino acid it is a structural component of
proteins, but it also plays a role as compatible solute under environmental stress conditions …

We review the mechanisms responsible for amino acid homeostasis in Saccharomyces
cerevisiae and other fungi. Amino acid homeostasis is essential for cell growth and survival …

Proline is an important amino acid in terms of its biological functions and biotechnological
applications. In response to osmotic stress, proline is accumulated in many bacterial and …

One of the central goals of evolutionary biology is to explain and predict the molecular basis
of adaptive evolution. We studied the evolution of genetic networks in Saccharomyces …

The limited therapeutic arsenal and the increase in reports of fungal resistance to multiple
antifungal agents have made fungal infections a major therapeutic challenge. The polyene …

The transportome of Saccharomyces cerevisiae comprises approximately 340 membrane-
bound proteins, of which very few are well-characterized. Elucidating transporter proteins' …

Extracellular signals regulate trafficking events to reorganize proteins at the plasma
membrane (PM); however, few effectors of this regulation have been identified. β-Arrestins …