Botulinum neurotoxins (BoNTs) are produced by anaerobic bacteria of the genus
Clostridium and cause a persistent paralysis of peripheral nerve terminals, which is known …

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins
known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as …

Botulinum neurotoxins are known to have seven serotypes (BoNT/A–G). Here we report a
new BoNT serotype, tentatively named BoNT/X, which has the lowest sequence identity with …

Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by
their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor …

Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of
potent bacterial toxins and potential bioterrorism agents. Here we report that an …

Botulinum neurotoxin injections are a valuable treatment modality for many therapeutic
indications and have revolutionized the field of aesthetic medicine so that they are the …

Recent developments in whole genome sequencing have made a substantial contribution to
understanding the genomes, neurotoxins and biology of Clostridium botulinum Group I …

Botulinum neurotoxins (BoNT) cause the disease botulism, a flaccid paralysis of the muscle.
They are also very effective, widely used medicines applied locally in sub-nanogram …

Abstract Tetanus (TeNT) and botulinum (BoNT) neurotoxins, the causative agents of tetanus
and botulism, respectively, are the most potent toxic molecules known to mankind. This …

Clostridial neurotoxins, including tetanus and botulinum neurotoxins, generally target
vertebrates. We show here that this family of toxins has a much broader host spectrum, by …