TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

Y Jiang, C Zhu, H Huang, G Huang, B Fu, X Xi - BMC cancer, 2023 - Springer
Background TUBA1C is an α-tubulin isoform involved in mitosis, and its dysregulation has
been implicated in tumor progression. There is still no clear understanding of its role in …

Predictive value of PIMREG in the prognosis and response to immune checkpoint blockade of glioma patients

H Zhu, X Hu, S Feng, L Gu, Z Jian, N Zou… - Frontiers in …, 2022 - frontiersin.org
Glioma is the most common primary brain tumor in the human brain. The present study was
designed to explore the expression of PIMREG in glioma and its relevance to the …

Transmembrane and coiled-coil domains 3 is a diagnostic biomarker for predicting immune checkpoint blockade efficacy in hepatocellular carcinoma

X Hu, H Zhu, S Feng, C Wang, Y Ye, X Xiong - Frontiers in Genetics, 2022 - frontiersin.org
Liver hepatocellular carcinoma (LIHC) is a malignancy with a high mortality and morbidity
rate worldwide. However, the pathogenesis of LIHC has still not been thoroughly studied …

ATP6V1F is a novel prognostic biomarker and potential immunotherapy target for hepatocellular carcinoma

X Hu, D Li, H Zhu, T Yu, X Xiong, X Xu - BMC Medical Genomics, 2023 - Springer
Hepatocellular carcinoma (HCC) is one of the deadliest malignancies worldwide, with late
detection, ineffective treatment and poor overall survival. Immunotherapy, including immune …

Identification of 3-Aryl-1-benzotriazole-1-yl-acrylonitrile as a Microtubule-Targeting Agent (MTA) in Solid Tumors

S Zoroddu, L Sanna, V Bordoni, L Weidong… - International Journal of …, 2024 - mdpi.com
Recently, a compound derived from recent scientific advances named 34 has emerged as
the focus of this research, the aim of which is to explore its potential impact on solid tumor …

Predictive value of procollagen c-protease enhancer protein on the prognosis of glioma patients

L Yu, X Hu, H Zhu - Heliyon, 2024 - cell.com
Procollagen c-protease enhancer protein (PCOLCE) performs an essential action in
improving the recreation of procollagen c-protease and promoting the reconstruction of …

[HTML][HTML] Comprehensive analysis to identify PUS7 as a prognostic biomarker from pan-cancer analysis to osteosarcoma validation

B Dong, B Wang, M Fan, J Zhang, Z Zhao - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Aim: Pseudouridylation has demonstrated the potential to control the development of
numerous malignancies. PUS7 (Pseudouridine Synthase 7) is one of the pseudouridine …

Development of DNA aptamers for visualization of glial brain tumors and detection of circulating tumor cells

AS Kichkailo, AA Narodov, MA Komarova… - … Therapy-Nucleic Acids, 2023 - cell.com
Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex
vivo, and in vivo for visualization diagnostics of central nervous system tumors. We selected …

System analysis based on the migration-and invasion-related gene sets identifies the infiltration-related genes of glioma

S Shi, J Zhong, W Peng, H Yin, D Zhong, H Cui… - Frontiers in …, 2023 - frontiersin.org
The current database has no information on the infiltration of glioma samples. Here, we
assessed the glioma samples' infiltration in The Cancer Gene Atlas (TCGA) through the …

Systematic pan-cancer analysis of the potential tumor diagnosis and prognosis biomarker P4HA3

Y Wu, B Zhang, J Nong, RA Rodrìguez, W Guo… - Frontiers in …, 2023 - frontiersin.org
Purpose: Prolyl 4-hydroxylase subunit alpha 3 (P4HA3) is implicated in several cancers'
development. However, P4HA3 has not been reported in other cancers, and the exact …