The diversity in the biological response of 4-thiazolidinones has attracted the attention of
many researchers to explore this framework for its potential. It is, therefore, of prime …

The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Highlights•We synthesized new diflunisal hydrazide–hydrazones.•We investigated their
activity against hepatitis C virus (HCV).•Some compounds exhibited strong inhibition against …

Hepatitis C virus (HCV) NS5B polymerase is a key target for the development of therapeutic
agents aimed at the treatment of HCV infections. Here we report on the identification of novel …

Abstract Hepatitis C virus (HCV) NS5B polymerase is an important and attractive target for
the development of anti-HCV drugs. Here we report on the design, synthesis and evaluation …

A series of novel N-(3-substituted aryl/alkyl-4-oxo-1, 3-thiazolidin-2-ylidene)-4-[5-(4-
methylphenyl)-3-(trifluoromethyl)-1 H-pyrazol-1-yl] benzenesulfonamides 2a–e were …

Hepatitis C virus (HCV) NS5B RNA polymerase is crucial for replicating the HCV RNA
genome and is an attractive target for developing anti-HCV drugs. A novel series of 2, 3 …

The synthesis of a new series of flurbiprofen hydrazide-hydrazones using
microwaveassisted reactions is described. Substituted aldehydes were condensed with …

Chronic infection by hepatitis C virus (HCV) often leads to severe liver disease including
cirrhosis, hepatocellular carcinoma and liver failure. Despite it being more than 20 years …

In continuation of our efforts to develop new derivatives as hepatitis C virus (HCV) NS5B
inhibitors, we synthesized novel 5‐arylidene‐4‐thiazolidinones. The novel compounds 29 …