The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It
can also be applied to cells isolated from treated animals. In this review, we highlight …

Heterocyclic polynuclear aromatic hydrocarbons (PAH) are characterized by higher
aqueous solubility and enhanced bioavailability due to presence of nitrogen, sulfur or …

Abstract The European Commission asked EFSA for a scientific evaluation on the risk to
human health of the presence of furan and methylfurans (2‐methylfuran, 3‐methylfuran and …

Abstract Furan (C4H4O) is a volatile, heterocyclic and carcinogenic heterocyclic chemical
compound occurring in a wide range of thermally processed foods. Several studies have …

Furan is a thermal food processing contaminant that is ubiquitous in various food products
such as coffee, canned and jarred foods, and cereals. A comprehensive summary of …

The reproductive toxicity associated with furan exposure in both animals and humans has
been documented. Protocatechuic acid (PCA), a dietary polyphenolic chemical, reportedly …

Exposure assessment is a fundamental part of the risk assessment paradigm, but can often
present a number of challenges and uncertainties. This is especially the case for process …

Furan is a widespread endogenous contaminant in heat-processed foods that can
accumulate rapidly in the food chain and has been widely detected in foods, such as wheat …

Furan is produced in a wide variety of heat-treated foods via thermal degradation. Furan
contamination is found to be relatively high in processed baby foods, cereal products, fruits …

Furan, a possible human carcinogen, is a product of incomplete combustion and is present
in cigarette smoke, engine exhaust, and processed food. Oral administration induces liver …