Despite conventional treatment options including chemoradiation, patients with the most
aggressive primary brain tumor, glioblastoma multiforme (GBM), experience an average …

Glioblastoma multiforme (GBM) is one of the most aggressive brain and spinal cord tumors.
Despite the significant development in application of antitumor drugs, no significant …

Background. The primary malignant brain tumor glioblastoma multiforme (GBM) is most
commonly detected in individuals over 60 years old. The standard therapeutic approach for …

Abstract Background Thymol (2-isopropyl-5-methylphenol) is a colorless crystalline
derivative of cymene, that possesses pleotropic pharmacological properties, including …

The substance P (SP)/neurokinin-1 receptor (NK-1R) system is involved in cancer
progression. NK-1R, activated by SP, promotes tumor cell proliferation and migration …

Cancer theragnostics is a novel approach that combines diagnostic imaging and
radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized …

Simple Summary Aiming to discover potential treatments for GBM, this review connects
emerging research on the roles of neurotransmitters in the normal neural and the GBM …

New, promising molecular targets to block tumor development and new compounds capable
of specifically destroying cancer cells must be urgently investigated. In recent years, the …

Glioma cells overexpress different peptide receptors that are useful for research, diagnosis,
management, and treatment of the disease. Oncogenic peptides favor the proliferation …

Abstract Treatment with chimeric antigen receptor (CAR) T cells indicated remarkable
clinical responses with liquid cancers such as hematological malignancies; however, their …