The evolution of the HIV-1 protease folding stability

D Ferreiro, R Khalil, MJ Gallego, NS Osorio… - Virus …, 2022 - academic.oup.com
The evolution of structural proteins is generally constrained by the folding stability. However,
little is known about the particular capacity of viral proteins to accommodate mutations that …

HIV-1 subtype diversity and factors affecting drug resistance among patients with virologic failure in antiretroviral therapy in Hainan province, China, 2014–2020

YU De E, YJ Xu, LI Mu, Y Yuan, HY Liang… - Biomedical and …, 2023 - Elsevier
Objective This study aimed to determine the HIV-1 subtype distribution and HIV drug
resistance (HIVDR) in patients with ART failure from 2014 to 2020 in Hainan, China …

Could long-acting cabotegravir-rilpivirine be the future for all people living with HIV? Response based on genotype resistance test from a multicenter Italian cohort

A De Vito, A Botta, M Berruti, V Castelli, V Lai… - Journal of Personalized …, 2022 - mdpi.com
Long-acting (LA) formulations have been designed to improve the quality of life of people
with HIV (PWH) by maintaining virologic suppression. However, clinical trials have shown …

Resistance rates among antiretroviral regimens in pregnant people living with HIV

MIF da Silveira Gouvêa… - HIV …, 2023 - Wiley Online Library
Objectives To update nucleoside reverse transcriptase inhibitor (NRTI), nonnucleoside
reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI) resistance rates and …

Development and validation of a scoring system for the prediction of HIV drug resistance in Hubei province, China

J Yan, W Zhang, H Luo, X Wang… - Frontiers in Cellular and …, 2023 - frontiersin.org
Objective The present study aimed to build and validate a new nomogram-based scoring
system for the prediction of HIV drug resistance (HIVDR). Design and methods Totally 618 …

Uso das profilaxias pós-exposição e pré-exposição no Brasil na prevenção combinada do HIV (2011-2019).

KC Ribeiro - 2022 - repositorio.ufmg.br
Introduction: The combination HIV prevention framework includes multiple interventions that
can be used to prevent HIV infeccion. HIV post-exposure prophylaxis (PEP) and HIV pre …