Hookworm infection is a major public health problem that threatens about 500 million people
throughout tropical areas of the world. Adult hookworms survive for many years in the host …

Helminthic parasites are important targets for vaccine research as they infect an estimated 1
billion people worldwide. Despite significant progress in the discovery of defined antigens …

Abstract Background Schistosomiasis caused by Schistosoma mansoni (Sm) is a chronic,
debilitating and potentially deadly neglected tropical disease. The licensure of a vaccine to …

Human hookworm, a soil-transmitted helminth (STH) infection caused by either Necator
americanus or Anclystoma duodenale, is a major cause of morbidity globally and …

Two malaria transmission-blocking vaccine (TBV) candidates, R0. 6C and ProC6C, have
completed preclinical development including the selection of adjuvants, Alhydrogel® with or …

My scientific life in translational medicine runs in two parallel, yet often converging paths.
The first, is four-decade-long commitment to develop new vaccines for parasitic and …

Background Human hookworms (Necator americanus, Ancylostoma duodenale, and
Ancylostoma ceylanicum) are intestinal blood-feeding parasites that infect~ 500 million …

Background Hookworm is a major contributor to worldwide disease burden with over 230
million people infected. It has been identified as one of the Neglected Tropical Diseases that …

Introduction As a primary stability-indicating parameter, potency should be strategically
evaluated during each phase of vaccine development. Herein, we present potency testing …

Nematodes are economically important parasites of many livestock species, while others are
important human pathogens causing neglected tropical diseases. In both humans and …