Abstract Poloxamer 407 copolymer (ethylene oxide and propylene oxide blocks) shows
thermoreversible properties, which is of the utmost interest in optimising drug formulation …

Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of
interest since the early 1980s. Advantages associated with buccal drug delivery have …

It is, sometimes, desirable to maintain a constant plasma drug concentration within the
therapeutically effective concentration range. The use of high viscosity hydromiscible …

Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene
oxide)(PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to …

The low solubility in biological fluids displayed by about 50% of the drugs still remains the
main limitation in oral, parenteral, and transdermal administration. Among the existing …

Block copolymers form a large number of superlattices with characteristic dimensions in the
range of a few nanometers up to several micrometers by self‐organization. The interplay of …

Pluronicв block copolymers are recognized pharmaceutical excipients listed in the US and
British Pharmacopoeia. The incorporation of drugs into Pluronic micelles results in …

Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …

Attempts at replicating physiological insulin secretion, as a means of restoring the normal
metabolic milieu and thereby minimizing the risk of diabetic complications, has become an …

In this work, we show that alteration of P407 gel content can affect drug release rates. The
inorganic salts and PEG 400 commonly included in the formulation of P407 gels can also …