Design considerations for hydrogel wound dressings: strategic and molecular advances

RC Op't Veld, XF Walboomers, JA Jansen… - … Engineering Part B …, 2020 - liebertpub.com
Wound dressings are traditionally used to protect a wound and to facilitate healing.
Currently, their function is expanding. There is an urgent need for new smart products that …

Signalling by transforming growth factor beta isoforms in wound healing and tissue regeneration

RWD Gilbert, MK Vickaryous… - Journal of developmental …, 2016 - mdpi.com
Transforming growth factor beta (TGFβ) signalling is essential for wound healing, including
both non-specific scar formation and tissue-specific regeneration. Specific TGFβ isoforms …

Down-Regulating Scar Formation by Microneedles Directly via a Mechanical Communication Pathway

Q Zhang, L Shi, H He, X Liu, Y Huang, D Xu, M Yao… - ACS …, 2022 - ACS Publications
Excessive extracellular matrix deposition drives fibroblasts into a state of high mechanical
stress, exacerbating pathological fibrosis and hypertrophic scar formation, leading to tissue …

Progress towards self-healing polymers for composite structural applications

M Scheiner, TJ Dickens, O Okoli - Polymer, 2016 - Elsevier
Repair in composite materials is tending towards autonomic healing systems. This is a
technological departure from the mechanical repair currently practiced in industry. For …

An anisotropic, hyperelastic model for skin: experimental measurements, finite element modelling and identification of parameters for human and murine skin

RB Groves, SA Coulman, JC Birchall… - Journal of the mechanical …, 2013 - Elsevier
The mechanical characteristics of skin are extremely complex and have not been
satisfactorily simulated by conventional engineering models. The ability to predict human …

A review of tendon injury: why is the equine superficial digital flexor tendon most at risk?

CT Thorpe, PD Clegg, HL Birch - Equine veterinary journal, 2010 - Wiley Online Library
Tendon injury is one of the most common causes of wastage in the performance horse; the
majority of tendon injuries occur to the superficial digital flexor tendon (SDFT) whereas few …

Electrospun biomaterials in the treatment and prevention of scars in skin wound healing

EJ Mulholland - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
Electrospinning is a promising method for the rapid and cost-effective production of
nanofibers from a wide variety of polymers given the high surface area morphology of these …

Biomechanics of scar tissue and uninjured skin

DT Corr, DA Hart - Advances in wound care, 2013 - liebertpub.com
Significance: Skin exhibits direction-dependent biomechanical behavior, influenced by the
structural orientation of its collagen-rich fibrous network and its viscous ground-substance …

Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model

CO Chantre, PH Campbell, HM Golecki, AT Buganza… - Biomaterials, 2018 - Elsevier
Wounds in the fetus can heal without scarring. Consequently, biomaterials that attempt to
recapitulate the biophysical and biochemical properties of fetal skin have emerged as …

Effect of human adipose derived stem cells on scar formation and remodeling in a pig model: a pilot study

IS Yun, YR Jeon, WJ Lee, JW Lee, DK Rah… - Dermatologic …, 2012 - Wiley Online Library
Background Adipose‐derived stem cells (ASC s) have positive effects in the wound healing
process. Objective To clarify whether ASC s positively mitigate scar formation in the wound …