Current status of obesity: Protective role of catechins

T Basu, A Selman, AP Reddy, PH Reddy - Antioxidants, 2023 - mdpi.com
Obesity is a growing health concern in today's society. Current estimates indicate that
obesity occurs in both adults and young people. Recent research also found that the …

Adenovirus 36 and obesity: an overview

E Ponterio, L Gnessi - Viruses, 2015 - mdpi.com
There is an epidemic of obesity starting about 1980 in both developed and undeveloped
countries definitely associated with multiple etiologies. About 670 million people worldwide …

The proposal of molecular mechanisms of weak organic acids intake-induced improvement of insulin resistance in diabetes mellitus via elevation of interstitial fluid pH

Y Marunaka - International Journal of Molecular Sciences, 2018 - mdpi.com
Blood contains powerful pH-buffering molecules such as hemoglobin (Hb) and albumin,
while interstitial fluids have little pH-buffering molecules. Thus, even under metabolic …

Twenty‐five years of research about adipogenic adenoviruses: A systematic review

M Akheruzzaman, V Hegde, NV Dhurandhar - Obesity Reviews, 2019 - Wiley Online Library
Infectious etiology is implicated in chronic diseases such as gastric ulcer or atherosclerosis.
However,“infection” is a recent term in the field of obesity. Since the first report in 1982 of …

Adenovirus type 36 regulates adipose stem cell differentiation and glucolipid metabolism through the PI3K/Akt/FoxO1/PPARγ signaling pathway

Y Jiao, X Liang, J Hou, Y Aisa, H Wu, Z Zhang… - Lipids in Health and …, 2019 - Springer
Background This study aims to investigate the molecular mechanism of Adenovirus type 36
(Ad36) in adipocyte differentiation and glucolipid metabolism. Methods Rat obesity model …

Hepatic expression of adenovirus 36 E4ORF1 improves glycemic control and promotes glucose metabolism through AKT activation

TB McMurphy, W Huang, R Xiao, X Liu… - Diabetes, 2017 - Am Diabetes Assoc
Considering that impaired proximal insulin signaling is linked with diabetes, approaches that
enhance glucose disposal independent of insulin signaling are attractive. In vitro data …

[PDF][PDF] Obesity and infection: reciprocal causality.

V Hainer, H Zamrazilová, M Kunešová… - Physiological …, 2015 - biomed.cas.cz
Associations between different infectious agents and obesity have been reported in humans
for over thirty years. In many cases, as in nosocomial infections, this relationship reflects the …

The human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinase

K Kong, M Kumar, M Taruishi, RT Javier - PLoS pathogens, 2014 - journals.plos.org
Adenoviruses infect epithelial cells lining mucous membranes to cause acute diseases in
people. They are also utilized as vectors for vaccination and for gene and cancer therapy, as …

Insulin sparing action of adenovirus 36 and its E4orf1 protein

NV Dhurandhar - Journal of Diabetes and its Complications, 2013 - Elsevier
Additional drugs are required to effectively manage diabetes and its complications. Recent
studies have revealed protective effects of Ad36, a human adenovirus, and its E4orf1 protein …

[HTML][HTML] E4orf1: The triple agent of adenovirus–Unraveling its roles in oncogenesis, infectious obesity and immune responses in virus replication and vector therapy

L Göttig, S Schreiner - Tumour Virus Research, 2024 - Elsevier
Abstract Human Adenoviruses (HAdV) are nearly ubiquitous pathogens comprising
numerous sub-types that infect various tissues and organs. Among many encoded proteins …