Research elucidating the pathogenesis of systemic lupus erythematosus (SLE) has defined
two critical families of mediators, type I interferon (IFN-I) and autoantibodies targeting nucleic …

Reports of widespread thromboses and disseminated intravascular coagulation (DIC) in
patients with coronavirus disease 19 (COVID-19) have been rapidly increasing in number …

Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which
may affect every organ and tissue. Genetic predisposition, environmental triggers, and the …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …

There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

The co-occurrence of diseases can inform the underlying network biology of shared and
multifunctional genes and pathways. In addition, comorbidities help to elucidate the effects …

Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …

Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease. Infections
or infectious reactivation are potential triggers for initiation of autoimmunity and for SLE …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) cases within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

A causal link between viral infections and autoimmunity has been studied for a long time
and the role of some viruses in the induction or exacerbation of systemic lupus …