Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities

L Belfiore, DN Saunders, M Ranson… - Journal of controlled …, 2018 - Elsevier
The development of therapeutic resistance to targeted anticancer therapies remains a
significant clinical problem, with intratumoral heterogeneity playing a key role. In this context …

Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies

S Mittal, H Kaur, N Gautam, AK Mantha - Biosensors and Bioelectronics, 2017 - Elsevier
Breast cancer is highly prevalent in females and accounts for second highest number of
deaths, worldwide. Cumbersome, expensive and time consuming detection techniques …

Electrochemical nanobiosensors for detection of breast cancer biomarkers

V Gajdosova, L Lorencova, P Kasak, J Tkac - Sensors, 2020 - mdpi.com
This comprehensive review paper describes recent advances made in the field of
electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as …

Quantitative digital histopathology and machine learning to predict pathological complete response to chemotherapy in breast cancer patients using pre-treatment …

K Saednia, A Lagree, MA Alera, L Fleshner, A Shiner… - Scientific Reports, 2022 - nature.com
Complete pathological response (pCR) to neoadjuvant chemotherapy (NAC) is a prognostic
factor for breast cancer (BC) patients and is correlated with improved survival. However …

Self-calibrating on-chip localized surface plasmon resonance sensing for quantitative and multiplexed detection of cancer markers in human serum

O Yavas, SS Acimovic, J Garcia-Guirado… - ACS …, 2018 - ACS Publications
The need for point-of-care devices able to detect diseases early and monitor their status, out
of a lab environment, has stimulated the development of compact biosensing configurations …

Expression of CDK8 and CDK8-interacting genes as potential biomarkers in breast cancer

EV Broude, B Gyorffy, AA Chumanevich… - Current cancer drug …, 2015 - ingentaconnect.com
CDK8 and its paralog CDK19, in complex with CCNC, MED12 and MED13, are
transcriptional regulators that mediate several carcinogenic pathways and the …

Challenges and opportunities in clinical applications of blood-based proteomics in cancer

R Bhawal, AL Oberg, S Zhang, M Kohli - Cancers, 2020 - mdpi.com
Simple Summary The traditional approach in identifying cancer related protein biomarkers
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …

Blood-based protein biomarkers in breast cancer

C Núñez - Clinica Chimica Acta, 2019 - Elsevier
Breast cancer (BCa) is a significant healthcare problem on women worldwide. Thus, early
detection is very important to reduce mortality. Furthermore, better BCa prognosis could …

Cadherins: the superfamily critically involved in breast cancer

M Afzal Ashaie… - Current pharmaceutical …, 2016 - ingentaconnect.com
Breast cancer, one of the leading causes of mortality and morbidity among females, is
regulated in part by diverse classes of adhesion molecules one of which is known as …

[HTML][HTML] Cancer: we should not forget the past

A Di Lonardo, S Nasi, S Pulciani - Journal of cancer, 2015 - ncbi.nlm.nih.gov
Cancer has been in existence longer than human beings, and man has been facing the
illness ever since he made his appearance on Earth. Amazingly, the first human cancer …