Role of hydrazine-related chemicals in cancer and neurodegenerative disease

PS Spencer, GE Kisby - Chemical Research in Toxicology, 2021 - ACS Publications
Hydrazine-related chemicals (HRCs) with carcinogenic and neurotoxic potential are found in
certain mushrooms and plants used for food and in products employed in various industries …

The application of nanotechnology in treatment of Alzheimer's disease

Y Cao, R Zhang - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
The buildup of beta-amyloid plaques in the brain results in Alzheimer's disease (AD), a
neurodegenerative condition. A permanent treatment for AD is not yet available. Only a …

Exogenous melatonin alleviates neuropathic pain-induced affective disorders by suppressing NF-κB/NLRP3 pathway and apoptosis

T Mokhtari, LP Yue, L Hu - Scientific reports, 2023 - nature.com
In this study, we aimed to evaluate the anti-inflammatory and anti-apoptotic effects of
melatonin (MLT) on neuropathic pain (NP)-induced anxiety and depression in a rat model …

Melatonin reduces oxidative stress in the right ventricle of newborn sheep gestated under chronic hypoxia

A Gonzaléz-Candia, PV Arias, SA Aguilar, EG Figueroa… - Antioxidants, 2021 - mdpi.com
Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition
involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of …

Genotoxic damage during brain development presages prototypical neurodegenerative disease

GE Kisby, PS Spencer - Frontiers in Neuroscience, 2021 - frontiersin.org
Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex
(ALS/PDC) is a disappearing prototypical neurodegenerative disorder (tau-dominated …

The role of Vitamin E–Selenium-Folic Acid Supplementation in Improving Sperm Parameters After Varicocelectomy: A Randomized Clinical Trial

AA Zadeh, D Arab, NS Kia, S Heshmati… - Urology …, 2019 - ojs3.sbmu.ac.ir
Purpose: In this study, we aimed to evaluate the effects of antioxidants including Vitamin E-
Selenium-Folic acid (Vit E-Se-FA) on semen parameters following varicocelectomy (VCT) …

Western Pacific ALS-PDC: Evidence implicating cycad genotoxins

PS Spencer, VS Palmer, GE Kisby - Journal of the neurological sciences, 2020 - Elsevier
Abstract Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex (ALS-PDC) is
a disappearing neurodegenerative disorder of apparent environmental origin formerly …

Exposure to blue LED light before the onset of darkness under a long‐day photoperiod alters melatonin secretion, feeding behaviour and growth in female dairy …

M Elsabagh, M Mon, Y Takao, A Shinoda… - Animal Science …, 2020 - Wiley Online Library
The effect of blue LED on melatonin secretion, feeding behaviour and growth was
addressed in Holstein female dairy calves. In Exp. 1, six animals (8 weeks old, 97±4.1 kg …

Dietary supplements in the management of varicocele‐induced infertility: A review of potential mechanisms

D Arab, H Doustmohammadi, A Ardestani Zadeh - Andrologia, 2021 - Wiley Online Library
Varicocele is a main cause of lower production of spermatozoon and infertility with multiple
pathophysiological mechanisms. In the past decades, the use of dietary supplements has …

[HTML][HTML] Effects of exogenous melatonin on MAM induced lung injury and lung development in mice offspring

M Azizi, P Pasbakhsh, M Sadr, T Mokhtari… - Tanaffos, 2020 - ncbi.nlm.nih.gov
Background: Melatonin as an antioxidant agent can have an effective role in lung
development. In this study, the effect of melatonin administration on lung injury in the …