Abstract The Rho GTPases—RHOA, RAC1 and CDC42—are small GTP binding proteins
that regulate basic biological processes such as cell locomotion, cell division and …

Cytokinesis mediates the physical separation of dividing cells after chromosome
segregation. In animal cell cytokinesis, a contractile ring, mainly composed of actin and …

Evolutionary expansion of the human neocortex reflects increased amplification of basal
progenitors in the subventricular zone, producing more neurons during fetal corticogenesis …

The human-specific gene ARHGAP11B is preferentially expressed in neural progenitors of
fetal human neocortex and increases abundance and proliferation of basal progenitors …

The actin cortex is a thin layer of actin, myosin and actin-binding proteins that underlies the
membrane of most animal cells. It is highly dynamic and can undergo remodelling on …

Cell division ends with the physical separation of the two daughter cells, a process known as
cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately …

The active form of the small GTPase RhoA is necessary and sufficient for formation of a
cytokinetic furrow in animal cells. Despite the conceptual simplicity of the process, the …

The GTPase RhoA promotes contractile ring assembly and furrow ingression during
cytokinesis. Although many factors that regulate RhoA during cytokinesis have been …

Many cells can generate complementary traveling waves of actin filaments (F-actin) and
cytoskeletal regulators. This phenomenon, termed cortical excitability, results from coupled …

The neocortex, the seat of our higher cognitive abilities, has expanded in size during the
evolution of certain mammals such as primates, including humans. This expansion occurs …