Mass drug administration (MDA) was a component of many malaria programs during the
eradication era, but later was seldomly deployed due to concerns regarding efficacy and …

Background Mass drug administration (MDA), defined as the empiric administration of a
therapeutic antimalarial regimen to an entire population at the same time, has been a …

Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …

Sepsis defined as a dysregulated immune response is a major cause of morbidity in
children. In sub-Saharan Africa, the clinical features of sepsis overlap with other frequent …

Seasonal malaria chemoprevention, previously known as intermittent preventive treatment
in children, is highly effective in areas with a short malaria transmission season. Here we …

Background In malaria endemic areas, pre‐school children are at high risk of severe and
repeated malaria illness. One possible public health strategy, known as Intermittent …

Background Intermittent preventive treatment of malaria in children less than five years of
age (IPTc) has been investigated as a measure to control the burden of malaria in the Sahel …

Background Previous studies have shown that in areas of seasonal malaria transmission,
intermittent preventive treatment of malaria in children (IPTc), targeting the transmission …

The past decade has seen an unprecedented surge in political commitment and
international funding for malaria control. Coverage with existing control methods (ie, vector …

Background Intermittent preventive treatment of malaria in children (IPTc) is a promising new
approach to the control of malaria in areas of seasonal malaria transmission but it is not …