Forensic molecular biomarkers for mixture analysis

F Oldoni, D Podini - Forensic Science International: Genetics, 2019 - Elsevier
The deconvolution of DNA mixtures has gathered the attention of forensic DNA scientists for
over two decades. To enhance mixture deconvolution capabilities, a new generation of …

Current and emerging tools for the recovery of genetic information from post mortem samples: New directions for disaster victim identification

J Watherston, D McNevin, ME Gahan, D Bruce… - Forensic Science …, 2018 - Elsevier
DNA profiling has emerged as the gold standard for the identification of victims in mass
disaster events providing an ability to identify victims, reassociate remains and provide …

Evaluation of the Illumina ForenSeq™ DNA Signature Prep Kit–MPS forensic application for the MiSeq FGx™ benchtop sequencer

C Xavier, W Parson - Forensic Science International: Genetics, 2017 - Elsevier
Abstract Massively Parallel (Next Generation) Sequencing (MPS) technologies have
recently been proven useful and successful in typing various markers relevant in forensic …

A sequence-based 74plex microhaplotype assay for analysis of forensic DNA mixtures

F Oldoni, D Bader, C Fantinato, SC Wootton… - Forensic Science …, 2020 - Elsevier
Microhaplotypes are emerging biomarkers for forensic applications. In this study, a
sequence-based multiplex assay of 74 microhaplotypes (230 SNPs) was developed on the …

Mixture deconvolution by massively parallel sequencing of microhaplotypes

L Bennett, F Oldoni, K Long, S Cisana… - International journal of …, 2019 - Springer
Short tandem repeat polymorphisms (STRs) are the standard markers for forensic human
identification. STRs are highly polymorphic loci analyzed using a direct PCR-to-CE (capillary …

Flanking region variation of ForenSeq™ DNA signature prep kit STR and SNP loci in Yavapai native Americans

FR Wendt, JL King, NMM Novroski, JD Churchill… - Forensic Science …, 2017 - Elsevier
Massively parallel sequencing (MPS) offers advantages over current capillary
electrophoresis-based analysis of short tandem repeat (STR) loci for human identification …

[HTML][HTML] Developmental validation of the ForenSeq MainstAY kit, MiSeq FGx sequencing system and ForenSeq universal analysis software

KM Stephens, R Barta, K Fleming, JC Perez… - Forensic Science …, 2023 - Elsevier
For human identification purposes, forensic genetics has primarily relied upon a core set of
autosomal (and to a lesser extent Y chromosome) short tandem repeat (STR) markers that …

STRait Razor Online: An enhanced user interface to facilitate interpretation of MPS data

JL King, AE Woerner, SN Mandape, KB Kapema… - Forensic Science …, 2021 - Elsevier
Abstract Since 2013, STRait Razor has enabled analysis of massively parallel sequencing
(MPS) data from various marker systems such as short tandem repeats, single nucleotide …

Increasing the discrimination power of ancestry-and identity-informative SNP loci within the ForenSeq™ DNA Signature Prep Kit

JL King, JD Churchill, NMM Novroski, X Zeng… - Forensic Science …, 2018 - Elsevier
The use of single nucleotide polymorphisms (SNPs) in forensic genetics has been limited to
challenged samples with low template and/or degraded DNA. The recent introduction of …

STRait Razor v2s: Advancing sequence-based STR allele reporting and beyond to other marker systems

JL King, FR Wendt, J Sun, B Budowle - Forensic Science International …, 2017 - Elsevier
STRait Razor has provided the forensic community a free-to-use, open-source tool for short
tandem repeat (STR) analysis of massively parallel sequencing (MPS) data. STRait Razor …