The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …

Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and …

Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …

Premature birth causes high rates of neonatal morbidity and mortality. There are multiple
causes of preterm birth. This article reviews the evidence linking subclinical infection and …

Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …

The elaboration of cytokines, chemokines and immunomodulatory proteins in the placenta
and gestational membranes has been extensively investigated in the context of both normal …

The fetal inflammatory response syndrome (FIRS) is a condition characterized by systemic
inflammation and an elevation of fetal plasma interleukin-6. This syndrome has been …

Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …

Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …

The regulatory signals responsible for the increased biosynthesis of prostaglandins during
parturition have not been established. Because interleukin-1 is capable of stimulating …