The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery

SE Grogans, E Bliss-Moreau, KA Buss, LA Clark… - Neuroscience & …, 2023 - Elsevier
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

[HTML][HTML] Identifying transdiagnostic mechanisms in mental health using computational factor modeling

T Wise, OJ Robinson, CM Gillan - Biological Psychiatry, 2023 - Elsevier
Most psychiatric disorders do not occur in isolation, and most psychiatric symptom
dimensions are not uniquely expressed within a single diagnostic category. Current …

[HTML][HTML] Transdiagnostic computations of uncertainty: towards a new lens on intolerance of uncertainty

TR Sandhu, B Xiao, RP Lawson - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
People radically differ in how they cope with uncertainty. Clinical researchers describe a
dispositional characteristic known as “intolerance of uncertainty”, a tendency to find …

The influence of anxiety on exploration: a review of computational modeling studies

KP Chou, RC Wilson, R Smith - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Exploratory behaviors can serve an adaptive role within novel or changing environments.
Namely, they facilitate information gain, allowing an organism to maintain accurate beliefs …

[HTML][HTML] Curiosity and the dynamics of optimal exploration

F Poli, JX O'Reilly, RB Mars, S Hunnius - Trends in Cognitive Sciences, 2024 - cell.com
What drives our curiosity remains an elusive and hotly debated issue, with multiple
hypotheses proposed but a cohesive account yet to be established. This review discusses …

Understanding the heterogeneity of anxiety using a translational neuroscience approach

CM Drzewiecki, AS Fox - Cognitive, Affective, & Behavioral Neuroscience, 2024 - Springer
Anxiety disorders affect millions of people worldwide and present a challenge in
neuroscience research because of their substantial heterogeneity in clinical presentation …

Understanding anxiety through uncertainty quantification

FE Hedley, E Larsen, A Mohanty… - British Journal of …, 2024 - Wiley Online Library
Uncertainty has been a central concept in psychological theories of anxiety. However, this
concept has been plagued by divergent connotations and operationalizations. The lack of …

A computational lens on the transdiagnostic nature of intolerance of uncertainty

T Sandhu, B Xiao, RP Lawson - 2022 - osf.io
People radically differ in how they cope with uncertainty. Clinical researchers describe a
dispositional characteristic known as “intolerance of uncertainty”, a tendency to find …

When in doubt average your priors: a latent cause model of risk and ambiguity aversion

E Le Lannou, R Dolan, G Story - 2024 - researchsquare.com
In decision-making, the likelihood of outcomes is often partly unknown, a form of uncertainty
known as ambiguity. Previous studies report that people tend to be averse to ambiguity …

The Role of Threat and Altered Inferential Processes in Delusions

E Larsen - 2024 - search.proquest.com
Delusions are a prominent, distressing, and sometimes treatment-resistant symptom of
psychotic disorders. Over three decades of experimental psychopathology work has been …