Objective: One of the most important side effects of opioids is their influence on the electrical
activity of the heart. This review focusses on the effects of opioids on QT interval …

Drug-induced prolongation of cardiac repolarization may trigger malignant ventricular
arrhythmias, such as torsade de pointes. The duration of QT interval, QT corrected for heart …

Background: The most common acquired cause of Long QT syndrome (LQTS) is drug
induced QT interval prolongation. It is an electrophysiological entity, which is characterized …

Long QT syndrome incidence is increasing in general population. A careful pre-, peri-and
post-operative management is needed for patients with this syndrome because of the risk of …

TORSADES DE pointes (TdP or “twisting of the points”) is a rare but potentially fatal
polymorphic ventricular tachycardia characterized by rapid, wide QRS complexes of …

Abstract Two emerging psychoactive substances, 2-(2, 5-dimethoxy-4-methylphenyl)-N-(2-
methoxybenzyl) ethanamine (25D-NBOMe) and N-(2-methoxybenzyl)-2, 5-dimethoxy-4 …

The use of many benzodiazepines is controlled worldwide due to their high likelihood of
abuse and potential adverse effects. Flubromazepam—a designer benzodiazepine—is a …

In recent years, several cases of torsade de pointes have been associated with many
opioids. However, to present no cases have been reported with tramadol. Objective: To …

Abstract Background/Purpose Mortality associated with prescription opioids has significantly
increased over the past few decades and is considered a global pandemic. Prescribed …

The long QT syndrome (LQTS) is a rare hereditary disorder in which affected individuals
have a possibility of ventricular tachyarrhythmia and sudden cardiac death. We investigated …