X-chromosome inactivation (XCI) is the epigenetic mechanism that ensures X-linked dosage
compensation between cells of females (XX karyotype) and males (XY). XCI is essential for …

The finding that transcription occurs at chromosome ends has opened new fields of study on
the roles of telomeric transcripts in chromosome end maintenance and genome stability …

Telomeres protect chromosome ends from nucleolytic degradation, uncontrolled
recombination by DNA repair enzymes and checkpoint signaling, and they provide …

TERRA is a class of telomeric repeat-containing RNAs that are expressed from telomeres in
multiple organisms. TERRA transcripts play key roles in telomere maintenance and their …

The function of TERRA in the regulation of telomerase in human cells is still debated. While
TERRA interacts with telomerase, how it regulates telomerase function remains unknown …

Abstract Alternative Lengthening of Telomeres (ALT) utilizes a recombination mechanism
and break-induced DNA synthesis to maintain telomere length without telomerase, but it is …

The telomeric noncoding RNA TERRA is a key component of telomeres and it is widely
expressed in normal as well as cancer cells. In the last 15 years, several publications have …

The subtelomeres, highly heterogeneous repeated sequences neighboring telomeres, are
transcribed into coding and noncoding RNAs in a variety of organisms. Telomereproximal …

Telomere repeat-containing RNA (TERRA) has been identified in multiple organisms
including Trypanosoma brucei, a protozoan parasite that causes human African …

Every year there is more and more evidence that non-coding RNAs play an important role in
biological processes affecting various levels of organization of living systems: from the …