Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate
intracellular signaling cascades that have important consequences for cellular behavior …

Lung cancer mortality represents the leading cause of cancer related deaths in the United
States and worldwide. Almost half of these deaths occur in female patients, making lung …

Background Previous studies that were based primarily on small numbers of patients
suggested that certain circulating proinflammatory cytokines may be associated with lung …

Purpose: Our previous study revealed that 90%[47 of 52; 95% confidence interval (CI), 0.79–
0.96] of Chinese never-smokers with lung adenocarcinoma harbor known oncogenic driver …

Heat shock protein 90 (Hsp90) is an evolutionary conserved molecular chaperone that,
together with Hsp70 and co-chaperones makes up the Hsp90 chaperone machinery …

Lung cancer (LC) is the leading cause of cancer death in men worldwide and has
significantly increased in women. Differences in non-small cell lung cancer (NSCLC) …

Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …

Objective Prenatal androgen exposure has been suggested to play a role in polycystic ovary
syndrome. Given the limited information on what maternal characteristics influence maternal …

Data analysis of clinical samples suggests that higher estrogen receptor α (ERα) expression
could be associated with worse overall survival in some patients with non‐small‐cell lung …

Purpose: The conversion of tumor cells from an epithelial to a mesenchymal-like phenotype,
via a process designated as the epithelial–mesenchymal transition (EMT), is known to …