Chemical ecology of antibiotic production by actinomycetes

A Van der Meij, SF Worsley… - FEMS microbiology …, 2017 - academic.oup.com
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

HU Van Der Heul, BL Bilyk, KJ McDowall… - Natural product …, 2018 - pubs.rsc.org
Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Evolution of high-level resistance during low-level antibiotic exposure

E Wistrand-Yuen, M Knopp, K Hjort… - Nature …, 2018 - nature.com
It has become increasingly clear that low levels of antibiotics present in many environments
can select for resistant bacteria, yet the evolutionary pathways for resistance development …

[HTML][HTML] Role of pollution on the selection of antibiotic resistance and bacterial pathogens in the environment

E Buelow, MC Ploy, C Dagot - Current Opinion in Microbiology, 2021 - Elsevier
Highlights•Pollution significantly increased since the industrial age and the introduction of
antimicrobial agents.•Pollution favours the selection of antibiotic resistance in the human …

Distribution of antibiotic resistance genes in soils and crops. A field study in legume plants (Vicia faba L.) grown under different watering regimes

F Cerqueira, V Matamoros, J Bayona, G Elsinga… - Environmental …, 2019 - Elsevier
Social concern has raised during the last years due to the development of antibiotic
resistance hotspots in different environmental compartments, including the edible parts of …

Microbial interactions trigger the production of antibiotics

T Netzker, M Flak, MKC Krespach, MC Stroe… - Current Opinion in …, 2018 - Elsevier
Since the discovery of penicillin, antibiotics have been instrumental in treating infectious
diseases. However, emerging antibiotic multi-resistance coinciding with a nearly exhausted …

Ecology determines how low antibiotic concentration impacts community composition and horizontal transfer of resistance genes

J Cairns, L Ruokolainen, J Hultman… - Communications …, 2018 - nature.com
Low concentrations of antibiotics have numerous effects on bacteria. However, it is unknown
whether ecological factors such as trophic interactions and spatial structuring influence the …

Antibiotic resistance genes distribution in microbiomes from the soil-plant-fruit continuum in commercial Lycopersicon esculentum fields under different agricultural …

F Cerqueira, V Matamoros, J Bayona, B Piña - Science of the Total …, 2019 - Elsevier
While the presence of antibiotic resistance genes (ARGs) in agricultural soils and products
has been firmly established, their distribution among the different plant parts and the …

Bacteria under antibiotic attack: Different strategies for evolutionary adaptation

EM Windels, B Van den Bergh, J Michiels - PLoS pathogens, 2020 - journals.plos.org
Bacteria are well known for their extremely high adaptability in stressful environments. The
clinical relevance of this property is clearly illustrated by the ever-decreasing efficacy of …

Bacterial outer membrane vesicles increase polymyxin resistance in Pseudomonas aeruginosa while inhibiting its quorum sensing

Z Chen, Y Liu, L Jiang, C Zhang, X Qian, J Gu… - Journal of Hazardous …, 2024 - Elsevier
The persistent emergence of multidrug-resistant bacterial pathogens is leading to a decline
in the therapeutic efficacy of antibiotics, with Pseudomonas aeruginosa (P. aeruginosa) …