Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …

Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During
stimulation, microglia undergo complex morphological changes, including loss of their …

Tryptophan metabolites are known to participate in the regulation of many cells of the
immune system and are involved in various immune-mediated diseases and disorders …

Detailed structural, biochemical, cell biological, and genetic studies of any gene/protein are
required to develop models of its actions in cells. Studying a protein family in the aggregate …

Background. Breast cancer is the most common cancer in Chinese women. Inflammation
contributes to tumor progression and can be induced by excessive production of pro …

Acute respiratory distress syndrome (ARDS) represents a significant burden to the
healthcare system, with≈ 200 000 cases diagnosed annually in the USA. ARDS patients …

Tumor necrosis factor (TNF) is a pleiotropic cytokine powerfully influencing diverse
processes of the central nervous system (CNS) under both physiological and pathological …

Over the last decade, danger-associated molecular pattern molecules, or alarmins, have
been recognized as signaling mediators of sterile inflammatory responses after trauma and …