Recently designated as a disorder in the DSM-5, premenstrual dysphoric disorder (PMDD)
presents an array of avenues for further research. PMDD's profile, characterized by cognitive …

Premenstrual dysphoric disorder (PMDD) is a severe mood disorder with core symptoms
(affective lability, irritability, depressed mood, anxiety) and increased sensitivity to stress …

In this article, we examine evidence supporting the role of reproductive steroids in the
regulation of mood and behavior in women and the nature of that role. In the first half of the …

In the early postpartum period, mother and infant navigate a critical neuroendocrine
transition from pregnancy to lactation. Two major clinical problems that occur during this …

Postpartum depression (PPD) affects up to 1 in 8 women. The early postpartum period is
characterized by a downward physiological shift from relatively elevated levels of sex …

Background About 5% of women experience severe symptoms called premenstrual
syndrome (PMS), only in the two weeks before their menstrual periods. Treatment with …

Stress and social isolation are well-known risk factors for psychopathology. However, more
research is needed as to the physiological mechanisms by which social support buffers the …

Animal models and a few human investigations suggest progesterone may be associated
with anxiety. Progesterone naturally fluctuates across the menstrual cycle, offering an …

Abstract Background: Allopregnanolone (3α-hydroxy-5α-pregnan-20-one) is a neurosteroid
which has an inhibitory function through interaction with the GABAA receptor. This …

Premenstrual dysphoric disorder (PMDD) is comprised of a cluster of affective, behavioral
and somatic symptoms recurring monthly during the luteal phase of the menstrual cycle. The …