Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Cardiac electrophysiological abnormalities in patients with cirrhosis

A Zambruni, F Trevisani, P Caraceni, M Bernardi - Journal of hepatology, 2006 - Elsevier
Abnormalities in cardiac electrophysiology are well documented in patients with liver
cirrhosis. The mechanisms underlying their occurrence are not fully understood, although it …

Protective role of CoQ10 or L-carnitine on the integrity of the myocardium in doxorubicin induced toxicity

HN Mustafa, GA Hegazy, SA El Awdan, M AbdelBaset - Tissue and Cell, 2017 - Elsevier
Doxorubicin (DOX) is a chemotherapeutic agent used for treatment of different cancers and
its clinical usage is hindered by the oxidative injury-related cardiotoxicity. This work aims to …

Cholestasis and endogenous opioids: liver disease and exogenous opioid pharmacokinetics

M Davis - Clinical pharmacokinetics, 2007 - Springer
A class of endogenous Opioids is upregulated in liver disease particular to cholestasis,
which contributes to symptoms in liver disease such as pruritus, hypotension and …

Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of …

D Saleh, M Abdelbaset, A Hassan, O Sharaf… - Plos one, 2020 - journals.plos.org
This study examines the protective effects of omega‐3 fatty acids (OMG), a frequently used
nutritional therapy in cancer patients, against doxorubicin (DOX)‐induced acute cardiorenal …

Cholestasis induces apoptosis in mice cardiac cells: the possible role of nitric oxide and oxidative stress

H Shafaroodi, F Ebrahimi, L Moezi… - Liver …, 2010 - Wiley Online Library
Abstract Background/Aims: Acute cholestasis is associated with cardiovascular
complications. The purpose of the present study was to investigate the effect of cholestasis …

Cardiovascular abnormalities in obstructive cholestasis: the possible mechanisms

L Moezi, AR Dehpour - Liver International, 2013 - Wiley Online Library
Cholestatic liver disease is associated with widespread derangements in the cardiovascular
system, such as bradycardia, hypotension, QT prolongation and peripheral vasodilation; it is …

Primary Protection of Diosmin Against Doxorubicin Cardiotoxicity via Inhibiting Oxido-Inflammatory Stress and Apoptosis in Rats

RS Abohashem, HH Ahmed, AH Sayed… - Cell Biochemistry and …, 2024 - Springer
Doxorubicin (DOX) is the cornerstone of chemotherapy. However, it has dose-dependent
cardiotoxic events that limit its clinical use. This study was intended to investigate the …

Involvement of opioidergic and nitrergic systems in memory acquisition and exploratory behaviors in cholestatic mice

M Nasehi, M Piri, K Abbolhasani… - Behavioural …, 2013 - journals.lww.com
Bile duct ligation (BDL) is an animal model used in cholestatic disease research. Both
opioidergic and nitrergic systems are known to be involved in cholestasis. The aim of this …

Cholestatic liver disease modulates susceptibility to ischemia/reperfusion-induced arrhythmia, but not necrosis and hemodynamic instability: the role of endogenous …

AR Hajrasouliha, S Tavakoli, P Jabehdar-Maralani… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Acute cholestasis is associated with cardiovascular complications,
which mainly manifest during stressful conditions. The goal of this study is to evaluate …