Parkinson's disease: etiopathogenesis and treatment

J Jankovic, EK Tan - Journal of Neurology, Neurosurgery & Psychiatry, 2020 - jnnp.bmj.com
The concept of 'idiopathic'Parkinson's disease (PD) as a single entity has been challenged
with the identification of several clinical subtypes, pathogenic genes and putative causative …

[HTML][HTML] An update on medical and surgical treatments of Parkinson's disease

D Nemade, T Subramanian, V Shivkumar - Aging and disease, 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is characterized by degeneration of dopaminergic neurons in the
substantia nigra pars compacta and other neuronal populations. The worldwide prevalence …

Dopamine and reward hypersensitivity in Parkinson's disease with impulse control disorder

DS Drew, K Muhammed, F Baig, M Kelly, Y Saleh… - Brain, 2020 - academic.oup.com
Impulse control disorders in Parkinson's disease are common neuropsychiatric
complications associated with dopamine replacement therapy. Some patients treated with …

Management of Impulse Control and Related Disorders in Parkinson's Disease: An Expert Consensus

I Debove, S Paschen, D Amstutz, F Cardoso… - Movement …, 2024 - Wiley Online Library
Background Impulse‐control and related behavioral disorders (ICBDs) significantly impact
the lives of Parkinson's disease (PD) patients and caregivers, with lasting consequences if …

Spectrum of impulse control behaviours in Parkinson's disease: pathophysiology and management

MJ Kelly, F Baig, MTM Hu, D Okai - Journal of Neurology …, 2020 - jnnp.bmj.com
Impulse control behaviours (ICBs) are a range of behaviours linked by their reward-based,
repetitive natures. They can be precipitated in Parkinson's disease (PD) by dopamine …

Impulse control disorders in Parkinson's disease: epidemiology, pathogenesis and therapeutic strategies

JF Zhang, XX Wang, Y Feng, R Fekete… - Frontiers in …, 2021 - frontiersin.org
Impulse control disorders (ICDs) in Parkinson's disease (PD) are aberrant behavior such as
pathological gambling, hypersexuality, binge eating, and compulsive buying, which typically …

The relationship between apathy and impulsivity in large population samples

P Petitet, J Scholl, B Attaallah, D Drew, S Manohar… - Scientific Reports, 2021 - nature.com
Apathy and impulsivity are debilitating conditions associated with many neuropsychiatric
conditions, and expressed to variable degrees in healthy people. While some theories …

Risk factors of impulsive-compulsive behaviors in PD patients: a meta-analysis

L Cao, T Xu, G Zhao, D Lv, J Lu, G Zhao - Journal of Neurology, 2022 - Springer
Objective To summarize the reliable risk factors of impulsive-compulsive behaviors (ICBs) in
Parkinson's disease (PD) patients through a meta-analysis on studies in which PD-ICBs …

Diagnostics and treatment of impulse control disorders, psychosis and delirium: systemic review-based recommendations-guideline “Parkinson's disease” of the …

K Witt, J Levin, T van Eimeren, A Hasan… - Journal of …, 2024 - Springer
Background and objective Impulse control disorders (ICD), psychosis and delirium are part
of the spectrum of behavioural changes associated with Parkinson's disease (PD). The …

An update on the use of non-ergot dopamine agonists for the treatment of Parkinson's disease

S Cerri, F Blandini - Expert Opinion on Pharmacotherapy, 2020 - Taylor & Francis
Introduction Long-term treatment of Parkinson's disease (PD) with levodopa is hampered by
motor complications related to the inability of residual nigrostriatal neurons to convert …