Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …

Combination therapies exploit the chances for better efficacy, decreased toxicity, and
reduced development of drug resistance and owing to these advantages, have become a …

Current cancer therapy includes a variety of strategies that can comprise only one type of
treatment or a combination of multiple treatments. Chemotherapy is still the gold standard for …

Rapidly growing resistance of pathogenic bacteria to conventional antibiotics leads to
inefficiency of traditional approaches of countering infections and determines the urgent …

This brief perspective article focuses on the most common errors and pitfalls, as well as the
do's and don'ts in drug combination studies, in terms of experimental design, data …

A generalized method for analyzing the effects of multiple drugs and for determining
summation, synergism and antagonism has been proposed. The derived, generalized …

Drug combinations have demonstrated great potential in cancer treatments. They alleviate
drug resistance and improve therapeutic efficacy. The fast-growing number of anti-cancer …

Fungal infection has become one of the leading causes of hospital-acquired infections with
high mortality rates. Furthermore, drug resistance is common for fungus-causing diseases …

Combination therapy has shown an obvious efficacy on complex diseases and can greatly
reduce the development of drug resistance. However, even with high-throughput screens …

Two goals motivate treating diseases with drug combinations: reduce off-target toxicity by
minimizing doses (synergistic potency) and improve outcomes by escalating effect …