Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

The metastatic spread of malignant cells to distant anatomical locations is a prominent
cause of cancer-related death. Metastasis is governed by cancer-cell-intrinsic mechanisms …

Originally described over a decade ago as a T cell transcription factor regulating T helper 1
cell lineage commitment, T-bet is now recognized as having an important role in many cells …

Simple Summary Innate immune natural killer (NK) cells are capable of killing metastatic
cancer cells without activation by antigen-presenting cells beforehand. The cytotoxic effects …

Abstract EOMES and T-BET are related T-box transcription factors that control natural killer
(NK) cell development. Here we demonstrate that EOMES and T-BET regulate largely …

A pigment-protein highly dominant in Spirulina is known as C-Phycocyanin. Earlier, in vitro
studies has shown that C-phycocyanin is having many biological activities like antioxidant …

T‐bet and Eomes are T‐box transcription factors that drive the differentiation and function of
cytotoxic lymphocytes such as NK cells. Their DNA‐binding domains are highly similar …

The T-box transcription factors T-bet and Eomesodermin (Eomes) have been well defined as
key drivers of immune cell development and cytolytic function. While the majority of studies …

The activation of immune-defense mechanisms in response to a microbial attack must be
robust and appropriately tailored to fight particular types of pathogens. Infection with …

Natural killer (NK) cell maturation is a tightly controlled process that endows NK cells with
functional competence and the capacity to recognize target cells. Here, we found that the …