Neuroblastoma (NB), the most common extracranial tumor of childhood, is a cancer of
primordial neural crest cells that give rise to sympathetic neural ganglia and adrenal …

Neuroblastoma, a neoplasm of the sympathetic nervous system, is the second most common
extracranial malignant tumor of childhood and the most common solid tumor of infancy …

Estimated 5‐year survival rates for patients with non‐high‐risk and high‐risk neuroblastoma
are 90% and 50%, respectively. Recent clinical trials have shown excellent outcomes with …

Background Outcomes for children with relapsed and refractory neuroblastoma are dismal.
The combination of irinotecan and temozolomide has activity in these patients, and its …

Abstract Purpose: Anti-GD2 mAbs, acting via antibody-dependent cell-mediated cytotoxicity,
may enhance the effects of chemotherapy. This pilot trial investigated a fixed dose of a …

Neuroblastoma, a neoplasm of the sympathetic nervous system, is the second most common
extracranial malignant tumor of childhood and the most common solid tumor of infancy …

The aim of this document is to provide general information about mIBG scintigraphy in
cancer patients. The guidelines describe the mIBG scintigraphy protocol currently used in …

Radiolabeled metaiodobenzylguanidine (mIBG) is a highly sensitive and specific marker for
detecting neuroblastoma. A semiquantitative mIBG score (Curie score [CS]) was assessed …

Criteria for evaluation of disease extent by 123I-metaiodobenzylguanidine scans in
neuroblastoma: a report for the International Neuroblastoma Risk Group (INRG) Task Force …

Purpose To evaluate the effect of disease sites and prior therapy on response and toxicity
after iodine-131-metaiodobenzylguanidine (131I-MIBG) treatment of patients with resistant …