Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of
reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed …

Nonenzymatic reactions of reducing sugars with primary amino groups of amino acids,
proteins, and nucleic acids, followed by oxidative degradations would lead to the formation …

Bioactive compounds from medicinal plants are good alternative treatments for T2DM. They
are also sources of lead molecules that could lead to new drug discoveries. In this study …

Background Advanced glycation end-products (AGEs) and their interaction with the receptor
for advanced glycation end-products (RAGE) play a pivotal role in the development and …

Diabetes and its complications, Alzheimer's disease (AD), and Parkinson's disease (PD) are
increasing gradually, reflecting a global threat vis‐à‐vis expressing the essentiality of a …

Obesity and type 2 diabetes mellitus (T2DM) are chronic pathologies with a high incidence
worldwide. They share some pathological mechanisms, including hyperinsulinemia, the …

Maillard reaction (MR) is a non-enzymatic browning reaction commonly seen in food
processing, which occurs between reducing sugars and compounds with amino groups …

Diabetic kidney disease (DKD) is one of the most common complications of diabetes, and its
prevalence is still growing rapidly. However, the efficient therapies for this kidney disease …

In hyperglycemic conditions, the level of reactive dicarbonyl metabolites concentration is
found to be high, which plays a significant role in protein glycation. Despite decades of …

Abstract Background and Aims In both type 1 diabetes (T1DM) and type 2 diabetes (T2DM),
previous studies have yielded inconsistent findings regarding whether the levels of the …