The synapsins are a family of neuronal phosphoproteins evolutionarily conserved in
invertebrate and vertebrate organisms. Their best-characterised function is to modulate …

Numerous data have been collected on lipid-binding amphipathic helices involved in
membrane-remodeling machineries and vesicular transport. Here we describe how, with …

HELIQUEST calculates the physicochemical properties and amino acid composition of an α-
helix and screens databank to identify protein segments possessing similar features. This …

Bacteria and eukaryotic cells contain geometry-sensing tools in their cytosol: protein motifs
or domains that recognize the curvature, concave or convex, deep or shallow, of lipid …

Two parameters of biological membranes, curvature and lipid composition, direct the
recruitment of many peripheral proteins to cellular organelles. Although these traits are often …

Abstract The Golgi-associated protein ArfGAP1 has an unusual membrane-adsorbing
amphipathic α-helix: its polar face is weakly charged, containing mainly serine and …

Lipids and several specialized proteins are thought to be able to sense the curvature of
membranes (MC). Here we used quantitative fluorescence microscopy to measure curvature …

Small G proteins play a central role in the organization of the secretory and endocytic
pathways. The majority of such small G proteins are members of the Rab family, which are …

All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …

Research investigating lipid membrane curvature generation and sensing is a rapidly
developing frontier in membrane physical chemistry and biophysics. The fast recent …