Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

Rat models of hormone receptor-positive breast cancer

R Nicotra, C Lutz, HA Messal, J Jonkers - Journal of Mammary Gland …, 2024 - Springer
Abstract Hormone receptor-positive (HR+) breast cancer (BC) is the most common type of
breast cancer among women worldwide, accounting for 70–80% of all invasive cases …

Chitosan-g-estrone Nanoparticles of Palbociclib Vanished Hypoxic Breast Tumor after Targeted Delivery: Development and Ultrasound/Photoacoustic Imaging

AK Mehata, V Singh, Vikas, N Singh… - … Applied Materials & …, 2023 - ACS Publications
Breast cancer is the leading cause of death among women globally. Approximately 80% of
all breast cancers diagnosed are overexpressed with estrogen receptors (ERs). In this study …

A network pharmacology-based approach to explore potential targets of Caesalpinia pulcherima: an updated prototype in drug discovery

NS Sakle, SA More, SN Mokale - Scientific reports, 2020 - nature.com
Caesalpinia pulcherima (CP) is a traditional herb used for the treatment of asthma,
bronchitis, cancer, anti-bacterial, anti-fungal and as abortifacient. In the present study …

Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and …

M Ginovyan, H Javrushyan, G Petrosyan… - … International Journal of …, 2023 - Elsevier
Cancer continues to be a leading cause of death worldwide, making the development of
new treatment methods crucial in the fight against it. With cancer incidence rates increasing …

Application of the Key Characteristics Framework to Identify Potential Breast Carcinogens Using Publicly Available in Vivo, in Vitro, and in Silico Data

JE Kay, JG Brody, M Schwarzman… - Environmental Health …, 2024 - ehp.niehs.nih.gov
Background: Chemicals that induce mammary tumors in rodents or activate estrogen or
progesterone signaling are likely to increase breast cancer (BC) risk. Identifying chemicals …

Multifaceted evaluation of pyrazole derivative (T4)-chitosan (CS) nanoparticles: Morphology, drug release, and anti-tumor efficacy in a rat model

R Murugan, SPRR Nayak, B Haridevamuthu… - International Journal of …, 2024 - Elsevier
The development of targeted nanotherapeutics has emerged as a pivotal advancement in
cancer treatment, aiming to enhance the efficacy and specificity of drug delivery while …

Therapeutic effect of simvastatin on DMBA‐induced breast cancer in mice

B Karimi, M Ashrafi, T Shomali… - Fundamental & clinical …, 2019 - Wiley Online Library
Preclinical studies have shown positive effects of statins against specific cancers. This study
aimed to determine the therapeutic effect of simvastatin in 12‐dimethylbenz (a) anthracene …

[HTML][HTML] Chitosan nanoplatform for the co-delivery of palbociclib and ultra-small magnesium nanoclusters: dual receptor targeting, therapy and imaging

AK Mehata, V Singh, P Srivastava, B Koch… - …, 2024 - ncbi.nlm.nih.gov
Theranostic nanoparticles have gained significant attention in cancer diagnosis and therapy.
In this study, estrone (ES) and folic acid (FA) functionalized single and dual receptor …

Zingiberene exerts chemopreventive activity against 7, 12‐dimethylbenz (a) anthracene‐induced breast cancer in Sprague‐Dawley rats

VD Seshadri, AAA Oyouni, WM Bawazir… - … of Biochemical and …, 2022 - Wiley Online Library
Breast cancer is the primary cause of cancer‐related death in females, wherein increased
mortality of breast cancer patients is recorded worldwide. Zingiberene is a monocyclic …