Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer

A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Aminoacyl-tRNA synthesis

M Ibba, D Söll - Annual review of biochemistry, 2000 - annualreviews.org
▪ Abstract Aminoacyl-tRNAs are substrates for translation and are pivotal in determining how
the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is …

Identification of an mRNP complex regulating tumorigenesis at the translational elongation step

GS Hussey, A Chaudhury, AE Dawson, DJ Lindner… - Molecular cell, 2011 - cell.com
Transcript-selective translational regulation of epithelial-mesenchymal transition (EMT) by
transforming growth factor-β (TGF-β) is directed by the hnRNP E1-containing TGF-β …

Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture

E Durr, J Yu, KM Krasinska, LA Carver… - Nature …, 2004 - nature.com
Endothelial cells can function differently in vitro and in vivo; however, the degree of
microenvironmental modulation in vivo remains unknown at the molecular level largely …

Modeling translation in protein synthesis with TASEP: A tutorial and recent developments

RKP Zia, J Dong, B Schmittmann - Journal of Statistical Physics, 2011 - Springer
The phenomenon of protein synthesis has been modeled in terms of totally asymmetric
simple exclusion processes (TASEP) since 1968. In this article, we provide a tutorial of the …

[HTML][HTML] CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division

I Groisman, YS Huang, R Mendez, Q Cao, W Theurkauf… - Cell, 2000 - cell.com
In Xenopus development, the expression of several maternal mRNAs is regulated by
cytoplasmic polyadenylation. CPEB and maskin, two factors that control polyadenylation …

[HTML][HTML] Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation

D Fagegaltier, N Hubert, K Yamada, T Mizutani… - The EMBO …, 2000 - embopress.org
Decoding of UGA selenocysteine codons in eubacteria is mediated by the specialized
elongation factor SelB, which conveys the charged tRNA Sec to the A site of the ribosome …

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease

S Gerstberger, M Hafner, M Ascano… - Systems biology of RNA …, 2014 - Springer
RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …

The origin of the eukaryotic cell: a genomic investigation

H Hartman, A Fedorov - Proceedings of the National …, 2002 - National Acad Sciences
We have collected a set of 347 proteins that are found in eukaryotic cells but have no
significant homology to proteins in Archaea and Bacteria. We call these proteins eukaryotic …

Translation initiation: structures, mechanisms and evolution

A Marintchev, G Wagner - Quarterly reviews of biophysics, 2004 - cambridge.org
Translation, the process of mRNA-encoded protein synthesis, requires a complex apparatus,
composed of the ribosome, tRNAs and additional protein factors, including aminoacyl tRNA …