Peripheral nerve injuries are common conditions with broad-ranging groups of symptoms,
depending on the severity and nerves involved. Although much knowledge exists on the …

Platelet-derived growth factor (PDGF) is a major mitogen for connective tissue cells and
certain other cell types. It is a dimeric molecule consisting of disulfide-bonded, structurally …

Peripheral nerve injury (PNI) is a major burden to society with limited therapeutic options,
and novel biomaterials have great potential for shifting the current paradigm of treatment …

Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Common etiologies of acute traumatic peripheral nerve injury (TPNI) include penetrating
injury, crush, stretch, and ischemia. Management of TPNI requires familiarity with the …

Whereas the central nervous system (CNS) usually cannot regenerate, peripheral nerves
regenerate spontaneously after injury because of a permissive environment and activation …

Vascular endothelial growth factor (VEGF) is a mitogen for endothelial cells, and it promotes
angiogenesis in vivo. Here we report that VEGF165 has neurotrophic actions on cultured …

Peripheral nerve injuries are common conditions with broad ranging groups of symptoms
depending on the severity and nerves involved. Although much knowledge exists on the …

We have used PCR to identify 13 novel protein-tyrosine kinase genes (tyro-1 to-13), six of
which (tyro-1 to-6). are preferentially expressed in the developing vertebrate nervous …