Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Exploring the relevance of senotherapeutics for the current SARS-CoV-2 emergency and similar future global health threats

M Malavolta, R Giacconi, D Brunetti, M Provinciali… - Cells, 2020 - mdpi.com
The higher death rate caused by COVID-19 in older people, especially those with
comorbidities, is a challenge for biomedical aging research. Here we explore the idea that …

[HTML][HTML] Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

O Rezahosseini, CH Drabe, SS Sørensen… - Transplantation …, 2019 - Elsevier
Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …

Torque teno virus viral load predicts SARS‐CoV‐2 vaccine response in kidney transplant recipients

M Solis, I Benotmane, F Gallais… - Journal of Medical …, 2023 - Wiley Online Library
Transplant recipients display poor responses to SARS‐CoV‐2 mRNA vaccines. In this
retrospective study, we investigate torque teno virus (TTV) viral load (VL), a ubiquitous virus …

Application of metagenomic next-generation sequencing in the diagnosis and treatment guidance of Pneumocystis jirovecii pneumonia in renal transplant recipients

F Zhang, J Chen, H Huang, X Deng, W Zhang… - European Journal of …, 2021 - Springer
Pneumocystis jirovecii pneumonia (PJP) is difficult to be diagnosed, so this study explored if
PJP could be diagnosed by metagenomic next-generation sequencing (mNGS) and if …

[HTML][HTML] Torque teno virus in liver diseases: On the way towards unity of view

VI Reshetnyak, IV Maev, AI Burmistrov… - World journal of …, 2020 - ncbi.nlm.nih.gov
The review presents the data accumulated for more than 20 years of research of torque teno
virus (TTV). Its molecular genetic structure, immunobiology, epidemiology, diagnostic …

Monitoring of Torque Teno virus DNAemia in critically ill COVID-19 patients: May it help to predict clinical outcomes?

L Forqué, E Albert, E Giménez, I Torres… - Journal of Clinical …, 2022 - Elsevier
Background: Torque teno virus (TTV) DNA load in plasma directly associates with the net
state of immunosuppression and inflammation in different clinical settings, including …

Plasma virome dynamics in chronic hepatitis B virus infected patients

M Thijssen, F Tacke, L Van Espen… - Frontiers in …, 2023 - frontiersin.org
The virome remains an understudied domain of the human microbiome. The role of
commensal viruses on the outcome of infections with known pathogens is not well …