COVID-19: breaking down a global health crisis

SI Mallah, OK Ghorab, S Al-Salmi, OS Abdellatif… - Annals of clinical …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

CTR Vegivinti, KW Evanson, H Lyons, I Akosman… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) continues to pose a significant
threat to public health worldwide. The purpose of this study was to review current evidence …

Hydroxychloroquine as pre-exposure prophylaxis for coronavirus disease 2019 (COVID-19) in healthcare workers: a randomized trial

R Rajasingham, AS Bangdiwala… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly
emerging virus causing the ongoing coronavirus disease 2019 (COVID-19) pandemic with …

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …

Therapy for early COVID-19: a critical need

PS Kim, SW Read, AS Fauci - Jama, 2020 - jamanetwork.com
While coronavirus disease 2019 (COVID-19) is predominantly self-limited, up to 20% of
symptomatic individuals will progress to severe or critical disease with clinical …

A living WHO guideline on drugs to prevent covid-19

F Lamontagne, M Stegemann, A Agarwal, T Agoritsas… - bmj, 2021 - bmj.com
Clinical question What is the role of drugs in preventing covid-19? Why does this matter?
There is widespread interest in whether drug interventions can be used for the prevention of …

Prophylaxis against covid-19: living systematic review and network meta-analysis

JJ Bartoszko, RAC Siemieniuk, E Kum, A Qasim… - Bmj, 2021 - bmj.com
Updates This is the second version (first update) of the living systematic review, replacing
the previous version (available as a data supplement). When citing this paper please …

Hydroxychloroquine as postexposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 infection: a randomized trial

RV Barnabas, ER Brown, A Bershteyn… - Annals of internal …, 2021 - acpjournals.org
Background: Effective prevention against coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently limited to …

COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease

R Fernandez-Ruiz, JL Paredes, TB Niewold - Translational Research, 2021 - Elsevier
As the world navigates the coronavirus disease 2019 (COVID-19) pandemic, there is a
growing need to assess its impact in patients with autoimmune rheumatic diseases, such as …

[HTML][HTML] Positive impact of oral hydroxychloroquine and povidone-iodine throat spray for COVID-19 prophylaxis: an open-label randomized trial

RCS Seet, AML Quek, DSQ Ooi, S Sengupta… - International Journal of …, 2021 - Elsevier
Background We examined whether existing licensed pharmacotherapies could reduce the
spread of coronavirus disease 2019 (COVID-19). Methods An open-label parallel …