Dopamine, affordance and active inference

KJ Friston, T Shiner, T FitzGerald… - PLoS computational …, 2012 - journals.plos.org
The role of dopamine in behaviour and decision-making is often cast in terms of
reinforcement learning and optimal decision theory. Here, we present an alternative view …

Cortical control of VTA function and influence on nicotine reward

J Wu, M Gao, JX Shen, WX Shi, AM Oster… - Biochemical …, 2013 - Elsevier
Tobacco use is a major public health problem. Nicotine acts on widely distributed nicotinic
acetylcholine receptors (nAChRs) in the brain and excites dopamine (DA) neurons in the …

Nonhuman gamblers: lessons from rodents, primates, and robots

F Paglieri, E Addessi, F De Petrillo, G Laviola… - Frontiers in behavioral …, 2014 - frontiersin.org
The search for neuronal and psychological underpinnings of pathological gambling in
humans would benefit from investigating related phenomena also outside of our species. In …

Are computational models of any use to psychiatry?

QJM Huys, M Moutoussis, J Williams - Neural Networks, 2011 - Elsevier
Mathematically rigorous descriptions of key hypotheses and theories are becoming more
common in neuroscience and are beginning to be applied to psychiatry. In this article two …

[图书][B] The neurobiology of criminal behavior: Gene-brain-culture interaction

A Walsh, JD Bolen - 2016 - taylorfrancis.com
The main feature of this work is that it explores criminal behavior from all aspects of
Tinbergen's Four Questions. Rather than focusing on a single theoretical point of view, this …

Impact of prefrontal cortex in nicotine-induced excitation of ventral tegmental area dopamine neurons in anesthetized rats

D Zhang, M Gao, D Xu, WX Shi, BS Gutkin… - Journal of …, 2012 - Soc Neuroscience
Systemic administration of nicotine increases dopaminergic (DA) neuron firing in the ventral
tegmental area (VTA), which is thought to underlie nicotine reward. Here, we report that the …

Drugs, crime, and the epigenetics of hedonic allostasis

A Walsh, H Johnson, JD Bolen - Journal of Contemporary …, 2012 - journals.sagepub.com
Given the relationship between drug abuse and criminal behavior, it is important for
criminologists to understand what drug addiction is and how it occurs. This article examines …

Critical role of computer simulations in drug discovery and development

P Srivastava, A Tiwari - Current Topics in Medicinal Chemistry, 2017 - ingentaconnect.com
The last couple of decades has witnessed that an amalgamation of multidisciplinary
branches of science come together in the form of 'Bioinformatics' and made a substantial …

Misdeed of the need: towards computational accounts of transition to addiction

M Keramati, SH Ahmed, BS Gutkin - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Reinforcement learning models link dopamine to acquisition of drug-oriented
behaviors.•Recent computational theory completes them by adding goal hierarchy and …

Policies and priors

K Friston - Computational neuroscience of drug addiction, 2012 - Springer
This chapter considers addiction from a purely theoretical point of view. It tries to
substantiate the idea that addictive behaviour is a natural consequence of abnormal …