Current status of animal models of posttraumatic stress disorder: behavioral and biological phenotypes, and future challenges in improving translation

J Deslauriers, M Toth, A Der-Avakian, VB Risbrough - Biological psychiatry, 2018 - Elsevier
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …

Chemical compositions and pharmacological activities of natural musk (Moschus) and artificial musk: A review

S Lv, Z Lei, G Yan, SA Shah, S Ahmed, T Sun - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Natural musk (Moschus), derived naturally from
male musk deer (Moschus berezovskii Flerov, Moschus sifanicus Przewalski, or Moschus …

Berberine and ginsenoside Rb1 ameliorate depression-like behavior in diabetic rats

JH Zhang, HZ Yang, H Su, J Song, Y Bai… - The American Journal …, 2021 - World Scientific
Rhizoma coptidis (Huang-lian) and Asian ginseng have been widely used in the treatment of
diabetes and other concurrent diseases with apparent effects. This study investigated the …

[HTML][HTML] Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis

X Li, T Wu, Z Yu, T Li, J Zhang, Z Zhang, M Cai… - Biomedicine & …, 2018 - Elsevier
Background Major depressive disorder (MDD) is a common but serious psychiatric disorder,
but current treatments are inadequate for approximately half of the patients with MDD. Thus …

The antidepressant-like effect of Ocimum basilicum in an animal model of depression

SS Ali, MG Abd El Wahab, NN Ayuob… - Biotechnic & …, 2017 - Taylor & Francis
We investigated the efficacy of Ocimum basilicum (OB) essential oils for treating depression
related behavioral, biochemical and histopathological changes caused by exposure to …

Can Ocimum basilicum relieve chronic unpredictable mild stress-induced depression in mice?

NN Ayuob, AEDL Firgany, AA El-Mansy, S Ali - Experimental and molecular …, 2017 - Elsevier
Background Depression is one of the important world-wide health problems. Objectives This
study aimed to assess the ameliorative effect of Ocimum basilicum (OB) essential oil on the …

Muscone ameliorates LPS-induced depressive-like behaviors and inhibits neuroinflammation in prefrontal cortex of mice

MC He, Z Shi, M Qin, NN Sha, Y Li, DF Liao… - The American Journal …, 2020 - World Scientific
Depression is partially caused by inflammation in the central nervous system. Early study
demonstrated that musk, glandular secretion from male musk deer, exerted an …

Ocimum basilicum improve chronic stress-induced neurodegenerative changes in mice hippocampus

NN Ayuob, MGA El Wahab, SS Ali… - Metabolic brain …, 2018 - Springer
Abstract Alzheimer's disease (AD), one of the progressive neurodegenerative diseases
might be associated with exposure to stress and altered living conditions. This study aimed …

Repetitive transcranial magnetic stimulation and fluoxetine attenuate astroglial activation and benefit behaviours in a chronic unpredictable mild stress mouse model …

Q Yuan, Y Lei, K Yu, J Wu, Z Xu, C Wen… - The World Journal of …, 2024 - Taylor & Francis
Objectives: Repetitive transcranial magnetic stimulation (rTMS) has been considered as an
effective antidepressant treatment; however, the mechanism of its antidepressant effect is …

Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review

K Liu, L Xie, M Deng, X Zhang, J Luo, X Li - Chinese medicine, 2021 - Springer
Musk, the dried secretion from the musk sac gland which is located between the navel and
genitals of mature male musk deer, is utilized as oriental medicine in east Asia. It has been …