Pathological and Therapeutical Implications of Pyroptosis in Psoriasis and Hidradenitis Suppurativa: A Narrative Review
PK Krajewski, M Tsoukas, JC Szepietowski - Current Issues in Molecular …, 2024 - mdpi.com
This manuscript explores the role of pyroptosis, an inflammatory programmed cell death, in
the pathogenesis of two chronic dermatoses, psoriasis and hidradenitis suppurativa (HS) …
the pathogenesis of two chronic dermatoses, psoriasis and hidradenitis suppurativa (HS) …
Zinc homeostasis regulates caspase activity and inflammasome activation
X Gong, W Gu, S Fu, G Zou, Z Jiang - PLoS pathogens, 2024 - journals.plos.org
Inflammasome activation drives pyroptotic cell death and the release of inflammatory
cytokines, and many diseases involve its overactivation. Zinc is essential for all organisms …
cytokines, and many diseases involve its overactivation. Zinc is essential for all organisms …
NLRP3 (rs10754558) gene polymorphism and tumor necrosis factor alpha as predictors for disease activity and response to methotrexate and adalimumab in …
FZ Kamel, HAM Hoseiny, AAE Shahawy, G Boghdadi… - Bmc Immunology, 2024 - Springer
Background Psoriasis has a global prevalence of 1–3%, with variations observed across
different ethnic groups and geographical areas. Disease susceptibility and response to anti …
different ethnic groups and geographical areas. Disease susceptibility and response to anti …
[HTML][HTML] NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study
A El Gendy, FHA Ali, SA Baioumy, SI Taha… - Immunobiology, 2025 - Elsevier
Background Chronic spontaneous urticaria (CSU) is a persistent skin condition with no
known cause or trigger. The unpredictability of CSU attacks lowers patients' quality of life …
known cause or trigger. The unpredictability of CSU attacks lowers patients' quality of life …
GSTP1 rs4147581 C> G and NLRP3 rs3806265 T> C as Risk Factors for Chronic Obstructive Pulmonary Disease: A Case-Control Study
H Li, R Wang, X Wei, C Zhang, W Pei… - … Journal of Chronic …, 2024 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a chronic respiratory ailment
influenced by a blend of genetic and environmental factors. Inflammatory response and an …
influenced by a blend of genetic and environmental factors. Inflammatory response and an …
Association of NLRP1 (rs878329) and NLRP3 (rs10754558) genes polymorphism in psoriasis vulgaris patients with dyslipidemia
AG Farag, EA Badr, NF Elnaidany, NM Gaafar… - Human Gene, 2022 - Elsevier
Introduction and aim NLRP inflammasome is intracellular sensors and not yet fully studied in
psoriasis vulgaris. The aim was to investigate the association of NLRP1 (rs878329) and …
psoriasis vulgaris. The aim was to investigate the association of NLRP1 (rs878329) and …