Common and uncommon mouse models of growth hormone deficiency

EO List, R Basu, DE Berryman, S Duran-Ortiz… - Endocrine …, 2024 - academic.oup.com
Mouse models of growth hormone deficiency (GHD) have provided important tools for
uncovering the various actions of GH. Nearly 100 years of research using these mouse lines …

Growth Hormone Receptor Antagonist Markedly Improves Gemcitabine Response in a Mouse Xenograft Model of Human Pancreatic Cancer

R Basu, P Kulkarni, D Swegan, S Duran-Ortiz… - 2024 - preprints.org
Chemotherapy treatment against pancreatic ductal adenocarcinoma (PDAC) is thwarted by
tumoral activation of multiple therapy-resistance pathways. The growth hormone (GH)–GH …

Characterizing Hormone Secretion Patterns in PitNETs with Metabolomics: Implications for Understanding Tumor Biology

F Köktaşoğlu, M Demirel, HD Ağaç, M Alim, U Sarıkaya… - 2024 - researchsquare.com
Background Pituitary neuroendocrine tumors (PitNETs) are heterogeneous neoplasms
originating from the pituitary gland. Metabolomics, a comprehensive analysis of small …