Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles

N van den Berg, M Rodríguez-Girondo… - Nature …, 2023 - nature.com
Globally, the lifespan of populations increases but the healthspan is lagging behind.
Previous research showed that survival into extreme ages (longevity) clusters in families as …

[HTML][HTML] Quantifying human genome parameters in aging

VP Volobaev, SS Kunizheva, LI Uralsky… - Vavilov Journal of …, 2023 - ncbi.nlm.nih.gov
Healthy human longevity is a global goal of the world health system. Determining the causes
and processes influencing human longevity is the primary fundamental goal facing the …

End of Life Events and Causes of Death in Danish Long-Lived Siblings: Reduced Dementia Risk Compared to Sporadic Long-Livers

A Galvin, JK Pedersen, KG Arbeev… - Journal of …, 2024 - content.iospress.com
Background: Better physical robustness and resilience of long-lived siblings compared to
sporadic long-livers has been demonstrated in several studies. However, it is unknown …

Increasing number of long-lived ancestors associates with up to a decade of healthspan extension and a healthy metabolomic profile in mid-life

N van den Berg, M Rodríguez-Girondo, IK van Dijk… - bioRxiv, 2022 - biorxiv.org
Globally, the lifespan of populations increases but the healthspan is lagging behind.
Previous research showed that survival into extreme ages (longevity) clusters in families as …

Developmental origins of exceptional health and survival: A four-generation family cohort study

MT Keys, DA Pedersen, PS Larsen, A Kulminski… - medRxiv, 2024 - medrxiv.org
Descendants of longevity-enriched sibships demonstrate a broad health and survival
advantage throughout the life course. However, little is known about manifestations during …

Количественные параметры генома человека при старении

ВП Волобаев, СС Кунижева… - … журнал генетики и …, 2023 - vavilov.elpub.ru
Аннотация Здоровое долголетие человека–глобальная цель мировой системы
здравоохранения. В то же время неуклонное старение населения стало серьезным …

[PDF][PDF] an den, Rodriguez-Girondo, M

N Berg - … , K., anssens,.. PO, Beekman, M., & …, 2020 - scholarlypublications …
Loci associated with longevity are likely to harbor genes coding for key players of molecular
pathways involved in a lifelong decreased mortality and decreased/compressed morbidity …