[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development

R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

The genetic architecture of aniridia and Gillespie syndrome

HN Hall, KA Williamson, DR FitzPatrick - Human Genetics, 2019 - Springer
Absence of part or all of the iris, aniridia, is a feature of several genetically distinct
conditions. This review focuses on iris development and then the clinical features and …

FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer

A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai… - Cancer cell, 2020 - cell.com
Mutations in the pioneer transcription factor FOXA1 are a hallmark of estrogen receptor-
positive (ER+) breast cancers. Examining FOXA1 in∼ 5,000 breast cancer patients identifies …

Quantitative profiling of BATF family proteins/JUNB/IRF hetero-trimers using Spec-seq

YK Chang, Z Zuo, GD Stormo - BMC Molecular Biology, 2018 - Springer
Background BATF family transcription factors (BATF, BATF2 and BATF3) form hetero-trimers
with JUNB and either IRF4 or IRF8 to regulate cell fate in T cells and dendritic cells in vivo …

[HTML][HTML] Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models

Y Zheng, GD Stormo, S Chen - bioRxiv, 2024 - ncbi.nlm.nih.gov
Paired-class homeodomain transcription factors (HD TFs) play essential roles in vertebrate
development, and their mutations are linked to human diseases. One unique feature of …