Insulin-like growth factor (IGF) performance in ovarian function and applications in reproductive biotechnologies

TB Piau, A de Queiroz Rodrigues, F Paulini - Growth Hormone & IGF …, 2023 - Elsevier
The role of the insulin-like growth factor (IGF) system has attracted close attention. The
activity of IGF binding proteins (IGFBPs) within the ovary has not been fully elucidated to …

Ovarian, uterine, and luteal vascular perfusions during follicular and luteal phases in the adult cyclic female rabbits with special orientation to their histological …

EA Abdelnaby, NAE Yasin, YS Abouelela… - BMC Veterinary …, 2022 - Springer
Understanding the does reproductive hemodynamic changes during the estrous cycle is
crucial for improving reproductive competence and fertility potential in this species. The …

IGF-1/IGF-1R/hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla

S Ma, G Liu, L Jin, X Pang, Y Wang, Z Wang, Y Yu… - Scientific Reports, 2016 - nature.com
Abstract Insulin-like growth factor-1 (IGF-1) and its receptor IGF-1R play a paramount role in
tooth/bone formation while hsa-let-7c actively participates in the osteogenic differentiation of …

Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its Target Igf1r in the Adult Rat Ovary

AA Martínez-Peña, K Lee, M Pereira, A Ayyash… - International Journal of …, 2022 - mdpi.com
As cannabis use during pregnancy increases, it is important to understand its effects on the
developing fetus. Particularly, the long-term effects of its psychoactive component, delta-9 …

Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor A (VEGFA) synergistically promote steroidogenesis and survival of cultured buffalo granulosa …

SR Mishra, J Bharati, G Rajesh, VS Chauhan… - Animal reproduction …, 2017 - Elsevier
The present study investigated the combined effect of fibroblast growth factor 2 (FGF2) and
vascular endothelial growth factor A (VEGF-A) on estradiol (E 2) secretion and relative …

In missed abortion the decrease of IGF-1 down-regulates PI3K/AKT signaling pathway reducing the secretion of progesterone and β-hCG

W Liang, T Zhu, N Tan, G Jing, Y Dang, Z Li - Growth Hormone & IGF …, 2022 - Elsevier
Objective To explore whether the reduction of IGF-1 in missed abortion down-regulates
PI3K/AKT signaling pathway, thereby causing trophoblast cell apoptosis and reducing the …

[HTML][HTML] Transcriptome profiling of different developmental stages of corpus luteum during the estrous cycle in pigs

J Bharati, NH Mohan, S Kumar, J Gogoi, S Kumar… - Genomics, 2021 - Elsevier
To better understand the molecular basis of corpus luteum (CL) development and function
RNA-Seq was utilized to identify differentially expressed genes (DEGs) in porcine CL during …

Stimulatory effect of luteinizing hormone, insulin-like growth factor-1, and epidermal growth factor on vascular endothelial growth factor production in cultured bubaline …

VS Chouhan, SS Dangi, V Babitha, MR Verma, S Bag… - Theriogenology, 2015 - Elsevier
The purpose of this study was to evaluate the temporal (24, 48, and 72 hours) and dose-
dependent (0, 5, 10, and 100 ng/mL of LH, insulin-like growth factor 1 [IGF-1], and EGF) in …

Expression and functional role of Bone Morphogenetic Proteins (BMPs) in cyclical corpus luteum in buffalo (Bubalus bubalis)

G Rajesh, A Paul, SR Mishra, J Bharati… - General and …, 2017 - Elsevier
The role of growth factors in the modulation of ovarian function is an interesting area of
research in reproductive biology. Recently, we have shown the expression and role of IGF …

Early growth response gene mediates in VEGF and FGF signaling as dissected by CRISPR in corpus luteum of water buffalo

M Punetha, VS Chouhan, A Sonwane, G Singh… - Scientific Reports, 2020 - nature.com
The EGR family comprises of EGR 1, EGR 2, EGR 3 and EGR 4 which are involved in the
transactivation of several genes. A broad range of extracellular stimuli by growth factors is …