Integrated MRI-guided radiotherapy—opportunities and challenges

PJ Keall, C Brighi, C Glide-Hurst, G Liney… - Nature Reviews …, 2022 - nature.com
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …

MR-guided radiotherapy for prostate cancer

BR Tocco, AU Kishan, TM Ma, LGW Kerkmeijer… - Frontiers in …, 2020 - frontiersin.org
External beam radiotherapy remains the primary treatment modality for localized prostate
cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent …

[HTML][HTML] Online adaptive radiotherapy potentially reduces toxicity for high-risk prostate cancer treatment

RL Christiansen, L Dysager, CR Hansen… - Radiotherapy and …, 2022 - Elsevier
Background and purpose With daily, MR-guided online adapted radiotherapy (MRgART) it
may be possible to reduce the PTV in pelvic RT. This study investigated the potential …

Recurrent endometrial cancer: local and systemic treatment options

H Rütten, C Verhoef, WJ van Weelden, A Smits… - Cancers, 2021 - mdpi.com
Simple Summary In this review, we discuss the different treatment strategies in recurrent
endometrial cancer. The incidence of endometrial cancer is rising. The available treatment …

Adaptive radiotherapy in the management of cervical cancer: review of strategies and clinical implementation

CE Shelley, LH Barraclough, CL Nelder, SJ Otter… - Clinical Oncology, 2021 - Elsevier
The complex and varied motion of the cervix–uterus target during external beam
radiotherapy (EBRT) underscores the clinical benefits afforded by adaptive radiotherapy …

[HTML][HTML] Initial feasibility and clinical implementation of daily MR-guided adaptive head and neck cancer radiation therapy on a 1.5 T MR-Linac system: prospective R …

BA McDonald, S Vedam, J Yang, J Wang… - International Journal of …, 2021 - Elsevier
Purpose This prospective study is, to our knowledge, the first report of daily adaptive
radiation therapy (ART) for head and neck cancer (HNC) using a 1.5 T magnetic resonance …

[HTML][HTML] Online adaptive MR-guided radiotherapy for rectal cancer; feasibility of the workflow on a 1.5 T MR-linac: clinical implementation and initial experience

MPW Intven, SRDM Van Otterloo, S Mook… - Radiotherapy and …, 2021 - Elsevier
Background and purpose Daily online adaptation of the clinical target volume (CTV) using
MR-guided radiotherapy enables margin reduction of the planning target volume (PTV). This …

Nanoparticles for MRI-guided radiation therapy: A review

L Smith, HL Byrne, D Waddington, Z Kuncic - Cancer Nanotechnology, 2022 - Springer
The development of nanoparticle agents for MRI-guided radiotherapy is growing at an
increasing pace, with clinical trials now underway and many pre-clinical evaluation studies …

ICRU REPORT 97: MRI-guided radiation therapy using MRI-linear accelerators

PJ Keall, CK Glide-Hurst, M Cao, P Lee… - Journal of the …, 2022 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

A national repository of complete radiotherapy plans: design, Results, and experiences

SL Krogh, C Brink, EL Lorenzen, E Samsøe… - Acta …, 2023 - Taylor & Francis
Background Previously, many radiotherapy (RT) trials were based on a few selected dose
measures. Many research questions, however, rely on access to the complete dose …