Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Senescent endothelial cells (ECs) could impair the integrity of the blood vessel endothelium,
leading to vascular aging and a series of diseases, such as atherosclerosis, diabetes …

Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …

Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …

Major depressive disorder (MDD) is a common and complex mental disorder, that adversely
impacts an individual's quality of life, but its diagnosis and treatment are not accurately …

Stroke is a leading cause of disability worldwide, and brain injuries devastate patients and
their families, but currently no drugs on the market promote neurological recovery. Limited …