Hydrogen atom transfer (HAT) is a salient feature of many enzymatic C–H cleavage
mechanisms. In systems where kinetic isolation of HAT is achieved, selective labeling of …

Polyethylene terephthalate (PET) has caused serious environmental concerns. Recent
studies show that a two-enzyme system in Ideonella sakaiensis is capable of degrading and …

The physical basis for enzymatic rate accelerations is a subject of great fundamental interest
and of direct relevance to areas that include the de novo design of green catalysts and the …

Despite increasing environmental concerns on ever-lasting Polyethylene Terephthalate
(PET), its global production is continuously growing. Effective strategies that can completely …

Soybean lipoxygenase (SLO) is a prototype for nonadiabatic hydrogen tunneling reactions
and, as such, has served as the subject of numerous theoretical studies. In this work, we …

Proton-coupled electron transfer (PCET) was studied in a series of tungsten hydride
complexes with pendant pyridyl arms ([(PyCH2Cp) WH (CO) 3], PyCH2Cp …

Our understanding of how enzymes work is coloured by static structure depictions where the
enzyme scaffold is presented as either immobile, or in equilibrium between well‐defined …

Lipoxygenase (LOX) enzymes produce important cell-signaling mediators, yet attempts to
capture and characterize LOX–substrate complexes by X-ray co-crystallography are …

A quantum mechanics/molecular mechanics (QM/MM) approach is a broadly used tool in
computational enzymology. Treating the QM region with a high-level DFT method is one of …

We report polymer-promoted cooperative catalysis of Cu for oxygen activation. A series of
random copolymers containing dipicolylamine as binding motifs are designed to coordinate …