Tissue factor and covid-19 associated thrombosis

N Mackman - Arteriosclerosis, Thrombosis, and Vascular Biology, 2024 - ahajournals.org
Microbial infections activate the innate and adaptive immune systems. Pathogen-associated
molecular patterns produced by microbes, such as double-stranded RNA, are detected by …

Extracellular vesicles for therapeutic nucleic acid delivery: loading strategies and challenges

A Oshchepkova, M Zenkova, V Vlassov - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released into the extracellular milieu by
cells of various origins. They contain different biological cargoes, protecting them from …

[HTML][HTML] Monocyte tissue factor expression: lipopolysaccharide induction and roles in pathological activation of coagulation

ATA Sachetto, N Mackman - Thrombosis and Haemostasis, 2023 - thieme-connect.com
The coagulation system is a part of the mammalian host defense system. Pathogens and
pathogen components, such as bacterial lipopolysaccharide (LPS), induce tissue factor (TF) …

Haemostatic Gene Expression in Cancer-Related Immunothrombosis: Contribution for Venous Thromboembolism and Ovarian Tumour Behaviour

V Tavares, J Savva-Bordalo, M Rei, J Liz-Pimenta… - Cancers, 2024 - mdpi.com
Simple Summary The exploration of prognostic biomarkers in ovarian cancer (OC) persists
due to the daunting challenge of therapy resistance and poor patient outcomes …

The association between mortality due to COVID-19 and coagulative parameters: a systematic review and meta-analysis study

A Abdollahi, S Nateghi, Z Panahi, SH Inanloo… - BMC Infectious …, 2024 - Springer
This systematic review and meta-analysis study evaluated the association between mortality
due to COVID-19 and coagulative factors. A systematic search was conducted on electronic …

Extracellular Vesicles and Their Role in Lung Infections

S Hambo, H Harb - International Journal of Molecular Sciences, 2023 - mdpi.com
Lung infections are one of the most common causes of death and morbidity worldwide. Both
bacterial and viral lung infections cause a vast number of infections with varying severities …

Lacticaseibacillus rhamnosus CRL1505 Peptidoglycan Modulates the Inflammation-Coagulation Response Triggered by Poly(I:C) in the Respiratory Tract

H Zelaya, L Arellano-Arriagada, K Fukuyama… - International Journal of …, 2023 - mdpi.com
Lacticaseibacillus rhamnosus CRL1505 beneficially modulates the inflammation-
coagulation response during respiratory viral infections. This study evaluated the capacity of …

Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma

B Wang, A Wöhler, J Greven, RJS Salzmann… - Frontiers in …, 2023 - frontiersin.org
Background Despite major advances in medicine, blood-borne biomarkers are urgently
needed to support decision-making, including polytrauma. Here, we assessed serum …

Annexin-V positive extracellular vesicles level is increased in severe COVID-19 disease

V Jacob, A Lambour, B Swinyard, Y Zerbib… - Frontiers in …, 2023 - frontiersin.org
Objectives To evaluate extracellular vesicles levels in a cohort of SARS-CoV-2's patients
hospitalized in an intensive care unit with and without COVID-19 associated …

Long Non-Coding RNAs: Bridging Cancer-Associated Thrombosis and Clinical Outcome of Ovarian Cancer Patients

IS Marques, V Tavares, J Savva-Bordalo, M Rei… - International Journal of …, 2023 - mdpi.com
Ovarian cancer (OC) and venous thromboembolism (VTE) have a close relationship, in
which tumour cells surpass the haemostatic system to drive cancer progression. Long non …