Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce
broken detailed balance at the molecular scale. This molecular scale breaking of detailed …

The cortex is a thin, crosslinked actin network lying immediately beneath the plasma
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …

Cytokinesis, the final step in cell division, partitions the contents of a single cell into two. In
animal cells, cytokinesis occurs through cortical remodeling orchestrated by the anaphase …

Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …

The ability of cells to divide asymmetrically is essential for generating diverse cell types
during development. The past 10 years have seen tremendous progress in our …

The actin cortex is a thin layer of actin, myosin and actin-binding proteins that underlies the
membrane of most animal cells. It is highly dynamic and can undergo remodelling on …

Cytokinesis, the physical separation of daughter cells at the end of mitosis, requires precise
regulation of the mechanical properties of the cell periphery,. Although studies of cytokinetic …

Asymmetric cell division (ACD) is an evolutionarily conserved mechanism used by
prokaryotes and eukaryotes alike to control cell fate and generate cell diversity. A detailed …

Mitotic spindle position defines the cell-cleavage site during cytokinesis. However, the
mechanisms that control spindle positioning to generate equal-sized daughter cells remain …